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NTHRYSInternshipsAi Bioprocess Optimization

Neural Network Surrogate Models for Bioprocesses

Ai Bioprocess Optimization
Neural Network Surrogate Models for Bioprocesses
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Neural Network Surrogate Models for Bioprocesses

Create computationally efficient deep learning surrogate models to replace expensive mechanistic simulations in bioprocess optimization workflows.

The focused areas below are internship topics in varied working formats. Pick one, then choose your internship type, mode… Read more

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📚 Academic: Thesis & PPT assistance included🧪 Tech: Master the protocols hands-on📝 Research > 3 months: Publication co-authorship in a Scopus-indexed journal
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Showing 110 of 10

Graph Neural Networks for Metabolic Pathway Prediction
This research investigates how graph neural networks can model complex metabolic networks and predict pathway dynamics in bioprocesses with unprecedented accuracy. The findings advance mechanistic understanding of cellular metabolism and enable rational design of engineered microorganisms for bioproduction.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £756
R · £1,100
3 Months
A · £994
T · £1,215
R · £1,767
6 Months
A · £2,209
T · £2,700
R · £3,927
14 more durationsView Titles →
Physics-Informed Neural Networks for Bioreactor Dynamics
This study explores integration of conservation laws and kinetic constraints into neural network architectures to model bioreactor behavior while maintaining physical interpretability. The contribution demonstrates how embedding domain knowledge improves generalization and reduces data requirements for bioprocess modeling.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £812
R · £1,181
3 Months
A · £1,067
T · £1,304
R · £1,897
6 Months
A · £2,371
T · £2,898
R · £4,215
14 more durationsView Titles →
Uncertainty Quantification in Surrogate Models of Cell Culture
This research develops Bayesian and ensemble approaches to rigorously quantify prediction uncertainty in neural network surrogates of mammalian and microbial cultures. The advancement enables probabilistic decision-making in bioprocess optimization and risk assessment for biotherapeutic manufacturing.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £784
R · £1,140
3 Months
A · £1,031
T · £1,260
R · £1,832
6 Months
A · £2,290
T · £2,799
R · £4,071
14 more durationsView Titles →
Transfer Learning Across Heterogeneous Bioprocess Datasets
This investigation examines how neural networks can leverage knowledge from diverse bioprocess platforms, fermentation, perfusion, fed-batch, to improve predictions on new or data-scarce processes. The scientific contribution reveals generalizable features of bioprocess dynamics that transfer across cultivation modes and organism types.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £772
R · £1,122
3 Months
A · £1,015
T · £1,240
R · £1,803
6 Months
A · £2,254
T · £2,755
R · £4,007
14 more durationsView Titles →
Attention Mechanisms for Temporal Dependencies in Fed-Batch Processes
This research applies transformer and attention-based architectures to capture long-range temporal correlations and dynamic feeding strategies in fed-batch bioprocesses. The discovery identifies critical time-dependent interactions that govern culture performance and enables adaptive control strategies.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £769
R · £1,118
3 Months
A · £1,011
T · £1,235
R · £1,796
6 Months
A · £2,245
T · £2,744
R · £3,991
14 more durationsView Titles →
Active Learning Strategies for Efficient Bioprocess Exploration
This study develops active learning frameworks that strategically select the most informative experimental conditions to train neural network surrogates with minimal resource expenditure. The contribution advances experimental design methodologies and accelerates discovery of optimal bioprocess parameters.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £735
R · £1,068
3 Months
A · £966
T · £1,180
R · £1,717
6 Months
A · £2,146
T · £2,623
R · £3,814
14 more durationsView Titles →
Multi-Task Learning for Coupled Bioprocess Outputs and Quality Attributes
This research explores multi-task neural architectures that simultaneously predict biomass, product titer, substrate consumption, and product quality metrics in integrated frameworks. The advancement reveals shared representations across bioprocess outputs and improves overall prediction robustness through learned regularization.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £818
R · £1,190
3 Months
A · £1,075
T · £1,314
R · £1,911
6 Months
A · £2,389
T · £2,920
R · £4,247
14 more durationsView Titles →
Recurrent Neural Networks for Real-Time Bioprocess State Estimation
This investigation develops LSTM and GRU-based surrogates to estimate unmeasured bioprocess states, intracellular metabolites, viability, stress markers, from sparse online sensor data. The scientific contribution enables soft-sensing capabilities that support real-time monitoring and model predictive control in biomanufacturing.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £738
R · £1,073
3 Months
A · £970
T · £1,185
R · £1,724
6 Months
A · £2,155
T · £2,634
R · £3,830
14 more durationsView Titles →
Mechanistic Interpretability of Neural Network Bioprocess Models
This research develops interpretability methods, saliency analysis, layer-wise relevance propagation, symbolic regression, to extract mechanistic insights from trained neural network surrogates. The contribution bridges machine learning and bioprocess engineering by connecting black-box predictions to underlying biophysical principles.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £796
R · £1,158
3 Months
A · £1,047
T · £1,280
R · £1,861
6 Months
A · £2,326
T · £2,843
R · £4,135
14 more durationsView Titles →
Hybrid Physics-Data Models for Scale-Up and Technology Transfer
This study integrates first-principles kinetic models with neural network correction terms to create hybrid surrogates that extrapolate reliably across bioreactor scales and geometries. The advancement addresses the critical challenge of bioprocess robustness during manufacturing scale-up and enables rational technology transfer protocols.
Academic (A)Tech (T)Research (R)
1 Month
A · £268
T · £833
R · £1,212
3 Months
A · £1,096
T · £1,339
R · £1,948
6 Months
A · £2,434
T · £2,975
R · £4,327
14 more durationsView Titles →